Dr. Udayan Apte, professor at the Department of Pharmacology, Toxicology and Therapeutics at KUMC studies mechanisms of normal and abnormal cell proliferation in the liver. He is investigating mechanisms of hepatocyte proliferation during liver development, liver regeneration and pathogenesis of liver cancers including hepatocellular carcinoma and hepatoblastoma (main liver cancer in the children). He is also investigating mechanisms of adverse effects of perfluoroalkyl substances (PFASs) on liver in children and adults. Finally, he is involved in a collaborative project with Dr. Voytek Slowik, a member of CHLN, investigating mechanism of pediatric nonalcoholic fatty liver disease. Dr. Apte utilizes cell specific transgenic mouse models of liver diseases and extensive next generation sequencing technology in his research work.